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Written by Dee Mani on 17 October 2025

Feeling Low? It Might Not Be Depression - It Might Be Deficiency.

The Modern Mood Crisis.

Honestly, the world has never looked so connected yet felt so disconnected. We can talk to anyone, anywhere, at any time - yet somehow, we’re more isolated than ever. The endless scroll, the fake smiles, the filtered lives - it’s all noise. Real connection, the kind that feeds your nervous system and calms your mind, has been replaced with digital chaos. No wonder so many people feel empty inside while looking like they have it all together.

Everywhere you look, people are popping pills, chasing dopamine hits, and quietly falling apart behind screens and smiles. Prescriptions for antidepressants are at an all-time high, yet depression, anxiety, and burnout are rising faster than ever. Something just doesn’t add up.

It's about time we admitted something extremely real - people don’t have a Prozac shortage, they have a life shortage. A shortage of rest, real food, real connection and a nervous system that actually feels safe. It’s not weakness - it’s biology begging for balance.

Your body was designed to regulate mood, energy, and motivation through an intricate network of systems. This includes neurotransmitters like serotonin and dopamine. It also involves your endocannabinoid system (ECS), the internal network that keeps everything in balance. But when those systems are depleted, overworked, and undernourished, your mood pays the price.

a person feeling very low and depressed but unsure whats going on

The Serotonin Myth That Sold the World a Lie

For decades, we were told depression was caused by “a chemical imbalance” — specifically, low serotonin. It became the perfect marketing story for antidepressants. Simple, sellablend scientifically… shaky.

In 2022, researchers at University College London published a landmark meta-analysis reviewing decades of data - and found no clear evidence that low serotonin causes depression. Even Harvard Health has acknowledged this "serotonin isn’t the villain, and depression isn’t a one-size-fits-all chemical problem."

Most people struggling with low mood aren’t chemically broken - they’re biologically starved. Their nervous system and brain chemistry are running on empty.

The Real Deficiency Epidemic

So what’s actually going wrong. Your mind is not betraying you, instead, your biology is crying out for balance.

1. Nutrient Gaps

This is one of the first places I think we should be looking when somebody suddenly doesn't feel like themselves. Low mood doesn't always arrive as sadness. Sometimes it's waking up exhausted despite sleeping. It's having no motivation, struggling to concentrate, feeling unusually anxious or irritable, losing interest in things you normally enjoy, or simply feeling completely flat.

And before assuming every one of those symptoms begins in the mind, we should at least ask whether the body actually has the raw materials it needs. Modern diets can leave us short of many of the nutrients involved in energy production, nervous system function, hormone balance and brain chemistry:

  • Magnesium - crucial for nervous system regulation, relaxation, sleep and our response to stress. When you're constantly stressed, your body's demand for magnesium can also increase.
  • Vitamin D3 and K2 – vitamin D is involved in brain function, immune regulation and mood, while K2 works alongside vitamin D in calcium regulation and bone health. They’re nutrients that make far more sense considered together than looking at vitamin D in isolation.
  • B12 and Folate - essential for healthy red blood cells, energy production and normal neurological function. Low levels can leave you exhausted, foggy and struggling to concentrate.
  • Iron, Ferritin and Copper – this is a big one, particularly for women. You can have haemoglobin within the “normal” range while your iron stores, measured by ferritin, are running low. But iron doesn’t work alone. Copper plays an important role in iron metabolism and is also needed for energy production, nervous-system function and neurotransmitter pathways. This is why simply taking more iron without looking at the wider mineral picture isn't always the answer. Low levels can show up as fatigue, weakness, poor concentration, headaches and that completely drained feeling that can easily affect your mood too.
  • Vitamin B6 - involved in making several neurotransmitters, including serotonin, dopamine and GABA. In other words, your brain needs nutrients to make the chemicals involved in mood in the first place.
  • Zinc - involved in hundreds of processes throughout the body, including immune function and normal brain signalling.
  • Omega-3 fats - your brain is an incredibly fatty organ. Healthy fats form part of cell membranes and are important for normal brain function and signalling.
  • Protein and amino acids - another one that gets overlooked. Neurotransmitters don't appear from nowhere. Your body uses amino acids from protein as building blocks for compounds involved in mood, motivation and sleep.

And then there's blood sugar.

If you're living on coffee, sugary snacks and ultra-processed carbohydrates, skipping meals and then wondering why you feel shaky, anxious, irritable, exhausted or unable to think straight, your body may simply be riding a metabolic rollercoaster all day.

We also need to think about the nutrients required for healthy thyroid function, because an underactive thyroid can bring fatigue, sluggishness, poor concentration and low mood with it. Iodine, selenium, iron and zinc all play roles in normal thyroid physiology.

This doesn't mean every person experiencing depression has a vitamin or mineral deficiency. Of course it doesn't. Mental health is far more complex than that. But if somebody is struggling, surely understanding what their body may be missing is crucial.

A 2020 review in Nutrients found associations between nutritional status, dietary patterns and mental health, adding to a growing body of research looking at the relationship between what we eat and how we feel. And this is why I don't like looking at mental health as though the brain somehow exists separately from the rest of the body.

Your brain has nutritional requirements too.

women with endocannabinoid deficiency struggling to  sleep

2. Endocannabinoid Deficiency

Here’s the missing piece almost nobody talks about. It's the most intelligent piece of physiology which was removed from the medical books in the early 1930's, but then rediscovered in the late 90's. It's the endocannabinoid system (ECS).

Your ECS is a vast internal network that helps regulate mood, stress, sleep, inflammation, and even emotional resilience. Your brain loses its ability to find homeostasis - balance when it’s depleted. Causes include stress, poor diet, toxins, trauma, or lack of sleep. A 2018 study in Frontiers in Immunology confirmed that ECS dysfunction is closely linked to mood disorders and stress response.

The word cannabinoid makes most people think of cannabis - but this system lives inside you. It’s your body’s own built-in regulator. Supporting it has nothing to do with getting high and everything to do with getting balanced.

How Modern Life Breaks Your Chemistry

If your mood’s been low, anxious, or flat-lined, it’s not random - it’s environmental.

  • Processed foods deplete vital nutrients.
  • Blue light and late nights wreck your circadian rhythm.
  • Constant stress floods your system with cortisol.
  • Emotional suppression keeps your nervous system in fight-or-flight mode.

And don't forget your gut, where 90% of serotonin is made. According to Harvard Health, gut inflammation has a direct effect on neurotransmitter production. This means that what is happening in your digestion is shaping your mood.

When your gut is inflamed, your ECS is suppressed, and your serotonin production slows. You don’t just feel tired - you feel numb.

Before You Assume It's All in Your Head

If you've been feeling unusually low, flat, anxious, exhausted or simply not like yourself, there are some very basic things worth investigating alongside your emotional health.

When did you last check your vitamin D, B12, folate, iron and ferritin? Are you eating enough protein and healthy fats? Are you sleeping properly? Are you getting outside? Are you constantly stressed? Is your blood sugar swinging all day? How is your gut? What about your thyroid? And importantly, what changed before you started feeling this way?

Medication can also affect nutrient status. So can restrictive diets, poor digestion, chronic stress, heavy periods, pregnancy, menopause, alcohol and simply eating a diet that contains plenty of calories but very little actual nutrition.

None of this dismisses genuine depression, trauma or emotional pain. Quite the opposite. Mental health deserves to be looked at properly — and that means looking at the whole person, not simply attaching a label to a collection of symptoms.

Because sometimes there is an emotional reason you're feeling low. Sometimes there is a physical reason. And very often, the two are connected.

Rebuilding Mood Naturally

The body’s design is genius — when given what it needs, it knows how to heal.

Feed the System, Don’t Fight It

Start by giving your cells the ingredients they crave:

  • Real food (not synthetic “energy” in a packet)
  • Daily sunlight exposure
  • Magnesium and omega-rich foods
  • Deep, consistent sleep
  • Movement that helps release emotion, not just burn calories

And then — support your ECS.

CBD is Nature’s Balancer

CBD doesn’t “fix” depression - it supports the very systems that regulate mood and emotional balance. Research suggests CBD may influence 5-HT1A serotonin receptors, helping your brain restore calm and resilience. A 2019 study in Molecular Neurobiology found CBD modulates serotonin signalling, which may contribute to mood stability.

CBD supports the ECS itself, the system that is your body’s internal peacekeeper. It helps to balance stress hormones over time. It also aids in managing inflammation. This is many people find that a consistent daily dose of high-quality Full Spectrum CBD oil helps them feel calmer. It makes them more balanced and emotionally centred. This all occurs without side effects or dependency.

At My Way CBD, our Full Spectrum Oils (500–6000mg) are formulated to support the body’s natural balance. They enhance stress resilience and promote everyday calm. However, it's important to recognise that consistency is key - think of it as nourishing your internal ecosystem back to equilibrium.

You’re Not Broken - You’re Underfed

The world tells you that depression is a flaw. I’m telling you - it’s feedback. Your body isn’t defective; it’s deficient. Deficient in sunlight, sleep and silence. Deficient in magnesium, connection, peace, and play.

When you start feeding your body what it’s been missing, your mood doesn’t need to be “managed.” This includes nutrients, cannabinoids, and real self-care. It naturally recalibrates.

If you’re ready to step off the rollercoaster, start rebuilding your mental health from the inside out. Grab our free Mental Health eBook. It’s packed with insights and natural strategies. These help support mood balance, repair the nervous system, and build emotional resilience. It does all this without the labels or side effects.

free Mental Health eBook

Written by Dee Mani

Dee Mani is the founder of My Way CBD, author of the bestselling book My Way, and a natural health consultant. Following a diagnosis of Triple Negative Breast Cancer in 2017, Dee chose a holistic approach focused on nutrition, lifestyle change, emotional wellbeing and plant medicine. After making a full recovery, she dedicated her life to helping others better understand the body, the endocannabinoid system, and the lifestyle factors that influence long-term health. Today, Dee educates thousands of people worldwide on CBD, cannabis, nervous system health, inflammation, hormones, trauma, nutrition and disease prevention. Through her writing, speaking and educational work, she is helping to change the conversation around natural health, personal responsibility and the body's remarkable ability to heal and maintain balance. Visit www.deemani.com to learn more.

FAQs

Q: Can CBD oil help with low mood?

A: CBD doesn’t treat or cure depression, but research suggests it may support the body’s endocannabinoid system, which influences mood, stress, and emotional balance.

Q: What strength of CBD is best for mood support?

A: Many people find 3000mg–6000mg Full Spectrum CBD oils supportive for mood balance. Start low and build gradually while monitoring how your body responds.

Q: How long before I notice results?

A: Some notice subtle calm within days; others take a few weeks. Like any nutrient, balance builds with consistency.

Q: Is CBD addictive?

A: No - CBD is non-addictive and non-intoxicating. It supports your natural equilibrium without altering your state of mind.

Q: Is CBD legal in the UK?

A: Yes, CBD is legal in the UK when derived from hemp and compliant with THC limits. My Way CBD products meet all UK regulatory standards.

Dislcaimer: This article is for educational purposes only and is not intended to diagnose, treat, or cure any medical condition.


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Written by Dee Mani on 17 October 2025
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